Enzyme-promoted regioselective coupling oligomerization of isorhapontigenin towards the first synthesis of (±)-gnetulin.

نویسندگان

  • Wenling Li
  • Shixia Yang
  • Teng Lv
  • Yadong Yang
چکیده

We report the first synthesis of a natural (±)-gnetulin and an unnatural analogue of (±)-gnemonol M by using the regioselective oxidative coupling reactions of 5-tert-butyl-isorhapontigenin as the key step. Both the effects of different enzyme-catalyzed systems on the structures of coupling products and structural transformations of coupling products in the presence of several Lewis acids were systematically investigated.

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عنوان ژورنال:
  • Organic & biomolecular chemistry

دوره 12 14  شماره 

صفحات  -

تاریخ انتشار 2014